Concomitant radiation therapy and paclitaxel for unresectable locally advanced breast cancer: results from two consecutive phase I/II trials.
Identifieur interne : 008015 ( Main/Exploration ); précédent : 008014; suivant : 008016Concomitant radiation therapy and paclitaxel for unresectable locally advanced breast cancer: results from two consecutive phase I/II trials.
Auteurs : Johnny Kao [États-Unis] ; Suzanne D. Conzen ; Nora T. Jaskowiak ; David H. Song ; Wendy Recant ; Rachana Singh ; Gregory A. Masters ; Gini F. Fleming ; Ruth HeimannSource :
- International journal of radiation oncology, biology, physics [ 0360-3016 ] ; 2005.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Antinéoplasiques d'origine végétale (usage thérapeutique), Association thérapeutique, Cicatrisation de plaie (effets des radiations), Femelle, Humains, Mammoplastie, Paclitaxel (usage thérapeutique), Radiodermite (étiologie), Récidive tumorale locale (), Sujet âgé, Tumeurs du sein (), Tumeurs du sein (radiothérapie), Tumeurs du sein (traitement médicamenteux).
- MESH :
- effets des radiations : Cicatrisation de plaie.
- radiothérapie : Tumeurs du sein.
- traitement médicamenteux : Tumeurs du sein.
- usage thérapeutique : Antinéoplasiques d'origine végétale, Paclitaxel.
- étiologie : Radiodermite.
- Adulte, Adulte d'âge moyen, Association thérapeutique, Femelle, Humains, Mammoplastie, Récidive tumorale locale, Sujet âgé, Tumeurs du sein.
English descriptors
- KwdEn :
- Adult, Aged, Antineoplastic Agents, Phytogenic (therapeutic use), Breast Neoplasms (drug therapy), Breast Neoplasms (radiotherapy), Breast Neoplasms (surgery), Combined Modality Therapy, Female, Humans, Mammaplasty, Middle Aged, Neoplasm Recurrence, Local (prevention & control), Paclitaxel (therapeutic use), Radiodermatitis (etiology), Wound Healing (radiation effects).
- MESH :
- chemical , therapeutic use : Antineoplastic Agents, Phytogenic, Paclitaxel.
- drug therapy : Breast Neoplasms.
- etiology : Radiodermatitis.
- prevention & control : Neoplasm Recurrence, Local.
- radiation effects : Wound Healing.
- radiotherapy : Breast Neoplasms.
- surgery : Breast Neoplasms.
- Adult, Aged, Combined Modality Therapy, Female, Humans, Mammaplasty, Middle Aged.
Abstract
The management of unresectable locally advanced breast cancer (ULABC) remains a major challenge because of the necessity both to treat local disease and to prevent distant disease. Two consecutive Phase I/II trials of concomitant chemotherapy and radiation (CRT) were performed to attempt to address both local and distant disease control in ULABC. This analysis focuses on rates of locoregional control and radiation-associated acute and late complications.
DOI: 10.1016/j.ijrobp.2004.07.714
PubMed: 15752883
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">The management of unresectable locally advanced breast cancer (ULABC) remains a major challenge because of the necessity both to treat local disease and to prevent distant disease. Two consecutive Phase I/II trials of concomitant chemotherapy and radiation (CRT) were performed to attempt to address both local and distant disease control in ULABC. This analysis focuses on rates of locoregional control and radiation-associated acute and late complications.</div>
</front>
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<name sortKey="Fleming, Gini F" sort="Fleming, Gini F" uniqKey="Fleming G" first="Gini F" last="Fleming">Gini F. Fleming</name>
<name sortKey="Heimann, Ruth" sort="Heimann, Ruth" uniqKey="Heimann R" first="Ruth" last="Heimann">Ruth Heimann</name>
<name sortKey="Jaskowiak, Nora T" sort="Jaskowiak, Nora T" uniqKey="Jaskowiak N" first="Nora T" last="Jaskowiak">Nora T. Jaskowiak</name>
<name sortKey="Masters, Gregory A" sort="Masters, Gregory A" uniqKey="Masters G" first="Gregory A" last="Masters">Gregory A. Masters</name>
<name sortKey="Recant, Wendy" sort="Recant, Wendy" uniqKey="Recant W" first="Wendy" last="Recant">Wendy Recant</name>
<name sortKey="Singh, Rachana" sort="Singh, Rachana" uniqKey="Singh R" first="Rachana" last="Singh">Rachana Singh</name>
<name sortKey="Song, David H" sort="Song, David H" uniqKey="Song D" first="David H" last="Song">David H. Song</name>
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<country name="États-Unis"><region name="Illinois"><name sortKey="Kao, Johnny" sort="Kao, Johnny" uniqKey="Kao J" first="Johnny" last="Kao">Johnny Kao</name>
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